Data detailed in “Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway” have been presented. “Curcumin, a component of turmeric, has been shown to suppress inflammation and angiogenesis largely by inhibiting the transcription factor nuclear factor-kappaB (NF-kappaB). This study evaluates the effects of curcumin on ovarian cancer growth using [...]

Scientists discuss in “Nonclassic endogenous regulators of angiogenesis” new findings in angiogenesis. According to recent research from Bari, Italy, “Angiogenesis, the process through which new blood vessels arise from preexisting ones, is regulated by several “classic” factors, among which the most studied are vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2). In recent [...]

Data detailed in “Antiangiogenic metronomic chemotherapy and hyperthermia in the palliation of advanced cancer” have been presented. According to a study from Italy, “Among a large series of cancer patients treated with a combination of chemotherapy and sessions of hyperthermia, particular attention was given to a specific group of patients with advanced cancer who refused [...]

Fresh data on angiogenesis are presented in the report “Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Contrary to initial expectations, angiogenesis inhibitors can cause toxicities in patients with cancer. The toxicity profiles of these inhibitors reflect the disturbance of growth factor signalling pathways that are important for maintaining homeostasis,” scientists in Utrecht, [...]

Scientists discuss in “Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development” new findings in angiogenesis. According to recent research published in the journal Cancer Research, “Blood and lymphatic vasculature are essential components of all organs, responsible for maintaining organ fluid dynamics and tissue homeostasis. Although both vessel systems are [...]

In PLoS Medicine, Nathan Ford and colleagues from the humanitarian agency Médecins Sans Frontières (MSF; Doctors Without Borders) describe their experience of providing HIV prevention and treatment in two prisons in Thailand.
HIV is more common among prisoners than among the general population of Thailand—one study, for example, in Klong Prem Central Prison, Bangkok, found that [...]

A survey of nearly 700 surgical residents in 17 U.S. medical centers finds that more than half failed to report needle-stick injuries involving patients whose blood could be a source of HIV, hepatitis and other infections.
Authors of the report — appearing in the June 28 issue of The New England Journal of Medicine — say [...]

Researchers at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences have patented a strategy for developing a human vaccine to prevent against Human Cytomegalovirus (hCMV) infection and disease.
CMV, a type of herpes virus, is the leading viral cause of birth defects and a serious problem in patients with compromised [...]

Althea Technologies, Inc., a leading provider of innovative technologies and services for pharmaceutical development and manufacturing, announced today that it has been engaged by GeoVax Labs, Inc. (OTC BB: GOVX), an Atlanta-based biotechnology company, to manufacturer its HIV-1 DNA (AIDS) vaccine. This vaccine will be utilized in GeoVax’s advanced Phase 2 human trials planned to [...]

Abbott’s Chairman and Chief Executive Officer Miles D. White joined Tanzania’s Minister of Health and Social Welfare the Hon. David Mwakyusa in Arusha today to dedicate the new Abbott Fund-supported laboratory at Mt. Meru Hospital. Mr. White also announced two new initiatives that will improve overall access to health care, and expand access to HIV [...]