Data detailed in “Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway” have been presented. “Curcumin, a component of turmeric, has been shown to suppress inflammation and angiogenesis largely by inhibiting the transcription factor nuclear factor-kappaB (NF-kappaB). This study evaluates the effects of curcumin on ovarian cancer growth using [...]

Scientists discuss in “Nonclassic endogenous regulators of angiogenesis” new findings in angiogenesis. According to recent research from Bari, Italy, “Angiogenesis, the process through which new blood vessels arise from preexisting ones, is regulated by several “classic” factors, among which the most studied are vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2). In recent [...]

Data detailed in “Antiangiogenic metronomic chemotherapy and hyperthermia in the palliation of advanced cancer” have been presented. According to a study from Italy, “Among a large series of cancer patients treated with a combination of chemotherapy and sessions of hyperthermia, particular attention was given to a specific group of patients with advanced cancer who refused [...]

Fresh data on angiogenesis are presented in the report “Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Contrary to initial expectations, angiogenesis inhibitors can cause toxicities in patients with cancer. The toxicity profiles of these inhibitors reflect the disturbance of growth factor signalling pathways that are important for maintaining homeostasis,” scientists in Utrecht, [...]

Scientists discuss in “Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development” new findings in angiogenesis. According to recent research published in the journal Cancer Research, “Blood and lymphatic vasculature are essential components of all organs, responsible for maintaining organ fluid dynamics and tissue homeostasis. Although both vessel systems are [...]